Description
Anastrozole is a potent, non-steroidal aromatase inhibitor used in the management of estrogen-sensitive conditions. It functions by selectively binding to the aromatase enzyme, which is responsible for converting androgens into estrogen throughout the body. By significantly reducing circulating estrogen levels, it addresses conditions driven by estrogen excess. Its primary clinical application is in the treatment of hormone receptor-positive breast cancer in postmenopausal women, but it is also utilized to manage and prevent estrogen-related side effects during anabolic steroid therapy.
Key Characteristics & Effects
Primary Benefits:
- Effectively lowers systemic estrogen levels
- Prevents and treats gynecomastia
- Reduces estrogen-related water retention
- Helps manage estrogen-driven fat storage
Common Side Effects:
- Can excessively suppress estrogen, leading to low-E2 symptoms
- May negatively impact cholesterol levels
- Can cause joint pain and dryness
- Potential for decreased bone mineral density with long-term use
Pharmacological Profile & Use
Anastrozole is administered orally and has a high bioavailability, with a half-life of approximately 50 hours, allowing for once-daily or even every-other-day dosing. Dosing must be carefully tailored based on ongoing blood work to maintain estrogen within a healthy range, avoiding both excess and deficiency. It does not have the progestogenic activity associated with some other aromatase inhibitors, making its action specific to estrogen control.
You can buy Anastrozole made by Apoxar in bulk in Canada via our website. Navigate to the “Purchase” tab and fill the contact form with details of your wholesale order. Please note: we do not sell single packs or ship directly to consumers, Apoxar is a wholesale fitness medication manufacturer and we work exclusively with our approved distributors.