GHRP-2 5 mg, 1 vial

Substance: Growth Hormone Releasing Peptide-2
Form: Lyophilized powder for reconstitution
Common names: GHRP-2
Dosage: 5 mg
Packaging: 1 vial
Purity: >99%

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Description

GHRP-2 (Growth Hormone-Releasing Peptide-2) is a potent synthetic hexapeptide and a powerful growth hormone secretagogue. It functions similarly to GHRP-6 by stimulating the pituitary gland to release a significant pulse of endogenous growth hormone (GH), but it is notably distinguished by its lack of the strong appetite-stimulating effect, making it a preferred choice for users seeking the metabolic and recovery benefits of elevated GH without increased hunger.

Mechanism of Action

The mechanism of action for GHRP-2 centers on its binding to the ghrelin receptor (GHSR-1a) in the hypothalamus and pituitary. This action potently stimulates the secretion of growth hormone in a synergistic manner with the body’s own Growth Hormone-Releasing Hormone (GHRH). Unlike GHRP-6, GHRP-2 has a significantly reduced effect on stimulating hunger hormones, as it does not cross the blood-brain barrier to the same degree to activate the hypothalamic feeding centers. This makes its action more selective for GH release.

Clinical Application and Dosage

GHRP-2 has been researched for potential therapeutic applications in growth hormone deficiency and as a diagnostic tool. In performance and physique enhancement, GHRP-2 is utilized to naturally elevate GH levels for its benefits in fat metabolism, skin and hair quality, improved sleep, enhanced recovery, and potential anti-aging effects, all without the complicating factor of excessive appetite.

Dosing of GHRP-2 follows research-based protocols, typically involving subcutaneous injection. Effective doses commonly range from 100 mcg to 300 mcg, administered two to three times per day. Optimal timing is typically on an empty stomach, post-workout, and before bedtime to align with the body’s natural GH pulses. The 5 mg vial of GHRP-2 supplies multiple doses and requires reconstitution with bacteriostatic water and subsequent refrigeration.

Treatment Protocol and Monitoring

Protocols with GHRP-2 can range from 3 to 6 months for sustained benefits. Due to its short half-life, multiple daily injections are required to achieve a pulsatile effect that mimics natural secretion. Monitoring is focused on subjective and objective outcomes such as improvements in body composition (fat loss), skin texture, sleep quality, and recovery rates. Users should also be aware of potential side effects related to elevated GH/IGF-1 levels.

Pharmacological Profile

GHRP-2 is a small peptide with a very short half-life, estimated at 15-30 minutes, necessitating frequent administration to maintain its stimulatory effect on GH pulses. It is administered via subcutaneous injection. Once reconstituted, the peptide is fragile and must be stored in a refrigerator to maintain stability. Its effects are transient and pulsatile, leading to a more physiological GH profile compared to exogenous GH injection.

Common Side Effects

While generally considered to have a cleaner side effect profile than GHRP-6 regarding hunger, GHRP-2 is still associated with side effects common to GH secretagogues. The most common include:

  • Transient Flushing and Warmth: A common feeling shortly after injection.
  • Mild Headache: Can occur post-injection, usually subsiding quickly.
  • Tingling or Numbness: Mild sensations in the hands or feet (paresthesia).
  • Carpal Tunnel Syndrome Symptoms: Numbness, tingling, or pain in the wrists and hands due to fluid retention and tissue growth from elevated GH/IGF-1.
  • Joint Aches and Water Retention: Symptoms associated with increased fluid retention and connective tissue growth.
  • Lethargy: Some users report temporary tiredness following administration.

As with any agent that elevates GH/IGF-1, there are theoretical long-term risks of insulin resistance and acromegaly-like symptoms with chronic, high-dose abuse. Its long-term safety profile is not fully established.

You can buy GHRP-2 made by Apoxar in bulk in Canada via our website. Navigate to the “Purchase” tab and fill the contact form with details of your wholesale order. Please note: we do not sell single packs or ship directly to consumers, Apoxar is a wholesale fitness medication manufacturer and we work exclusively with our approved distributors.

GHRP-2 FAQ

What is GHRP-2 and what does it do?

GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic peptide that strongly stimulates the pituitary gland to release pulses of natural growth hormone. It works by mimicking the action of ghrelin, the "hunger hormone," binding to its receptor to induce a significant GH pulse.

What are its primary uses and benefits?

Its primary uses are to elevate growth hormone levels to support muscle growth, accelerate recovery from training, enhance fat loss, and improve sleep quality. It is valued for its potent and reliable GH-releasing effect.

How is it dosed and administered?

It is administered via subcutaneous injection, typically 2-3 times per day (e.g., post-workout, pre-bed). Common doses range from 100-300 mcg per injection. The 5 mg multi-dose vial allows for precise reconstitution and consistent daily dosing over a cycle.

Are there any notable side effects?

The most common side effect is a significant increase in appetite immediately after injection due to its ghrelin-like activity. Mild water retention or tingling in the extremities may also occur initially. It can temporarily elevate cortisol and prolactin levels.

Why is pharmaceutical-grade purity essential for this peptide?

Potency and receptor specificity are critical for a predictable hormonal response. Apoxar's GMP-certified synthesis ensures the exact 5 mg peptide content, correct amino acid sequence, and a sterile, endotoxin-free product, guaranteeing both safety and efficacy.

Should it be used alone or with a GHRH (like CJC-1295)?

While effective solo, GHRP-2 is most powerful when combined with a Growth Hormone Releasing Hormone (GHRH) like CJC-1295 (without DAC). The GHRH provides the "signal" to produce GH, while GHRP-2 provides the potent "pulse," creating a strong synergistic release that mimics the body's natural secretion.

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