Description

HGH-176-191 is a synthetic fragment of the endogenous human growth hormone (HGH), comprising the amino acid sequence 176-191 of its C-terminus. This specific fragment is engineered to isolate and amplify the potent fat-burning (lipolytic) properties of growth hormone while intentionally removing its anabolic, growth-promoting, and insulin-resistant effects. HGH-176-191 is thus a specialized peptide used primarily for targeted fat loss and metabolic enhancement.

Mechanism of Action

The mechanism of action for HGH-176-191 is highly selective. It mimics the portion of the growth hormone molecule responsible for signaling fat cells (adipocytes) to break down stored triglycerides into free fatty acids—a process called lipolysis. Unlike full-length GH, HGH-176-191 does not bind to growth hormone receptors that stimulate IGF-1 production or protein synthesis. This allows it to selectively promote fat oxidation and inhibit the formation of new fat tissue without causing water retention, joint pain, or significant impacts on blood sugar that are characteristic of full HGH therapy.

Clinical Application and Dosage

HGH-176-191 is a research peptide with no approved therapeutic indications. Its application is centered entirely on body composition enhancement, where it is used as a cutting agent to promote stubborn fat loss, particularly in areas like the abdomen, without the risk of gaining muscle mass or the high cost associated with full HGH cycles.

Dosing of HGH-176-191 is based on its short half-life and requires frequent administration. Common research protocols involve subcutaneous injections of 200 mcg to 500 mcg, administered two to three times per day. Injections are ideally timed before periods of fasting or low food intake (e.g., upon waking and before bed) and at least a few hours after meals to maximize fat-burning. The 5 mg vial of HGH-176-191 provides multiple doses and must be reconstituted with bacteriostatic water and stored refrigerated.

Treatment Protocol and Monitoring

Cycles with HGH-176-191 are typically run for 6 to 12 weeks. Its effects on fat loss are gradual but cumulative, working best when combined with a caloric deficit and exercise. Monitoring is primarily focused on changes in body composition, measurements of stubborn fat areas, and overall weight. Due to its targeted mechanism, there is less need for the extensive blood work monitoring required for full HGH, though general health markers should always be observed.

Pharmacological Profile

HGH-176-191 is a small peptide with a very short half-life, estimated at 30 minutes or less. This necessitates multiple daily injections to maintain its lipolytic signal. It is administered via subcutaneous injection, often in the abdominal region, though systemic effects are not localized to the injection site. Once reconstituted, it is stable for a limited time when refrigerated.

Common Side Effects

Due to its selective action, HGH-176-191 has a notably cleaner side effect profile compared to full HGH or other anabolic agents. However, some side effects are possible, including:

• Localized Lipoatrophy: Rare but possible if injected repeatedly in the exact same spot, as it can break down subcutaneous fat tissue unevenly.
• Increased Hunger: A minority of users report an increase in appetite.
• Mild Headache or Nausea: Usually transient and dose-dependent.
• Tingling Sensations: Some users report a mild, transient tingling in the extremities, possibly related to increased fat metabolism.
• Hypoglycemia Risk: Extremely low compared to full GH, but a theoretical risk if used in very high doses, as it can increase insulin sensitivity.

The most significant advantage of HGH-176-191 is the absence of common HGH side effects: no joint pain, no carpal tunnel syndrome, no significant water retention, and no organ growth. It is considered a lower-risk option for fat loss within the peptide category, though its long-term safety profile is not fully established.

You can buy HGH-176-191 made by Apoxar in bulk in Canada via our website. Navigate to the “Purchase” tab and fill the contact form with details of your wholesale order. Please note: we do not sell single packs or ship directly to consumers, Apoxar is a wholesale fitness medication manufacturer and we work exclusively with our approved distributors.