Description

Metenolone is an orally active, dihydrotestosterone (DHT)-derived anabolic steroid known for its mild yet high-quality anabolic properties and very low androgenic activity. As the oral form of Primobolan, Metenolone is prized for promoting lean, hard, and sustainable muscle gains with an exceptionally favorable side effect profile, making it suitable for longer cycles and those sensitive to stronger androgens.

Mechanism of Action

The mechanism of action for Metenolone involves its binding to androgen receptors, stimulating protein synthesis and nitrogen retention. Its DHT-based structure prevents aromatization, completely eliminating the risk of estrogenic side effects such as water retention or gynecomastia. Furthermore, Metenolone exhibits minimal hepatotoxicity compared to most other 17-alpha-alkylated oral steroids due to its 1-methylation. This results in a clean anabolic effect that promotes dense muscle tissue without significant water or fat gain.

Clinical Application and Dosage

Metenolone has been used clinically to treat conditions involving muscle wasting and anemia. In performance and physique enhancement, oral Metenolone is favored during cutting phases, lean mass accrual periods, or by individuals seeking gentle yet consistent results with minimal strain on the body. Its mild nature often requires higher dosages to see significant effects, which increases cost.

The dosage of oral Metenolone is notably higher than more potent orals due to its mildness. For men, effective doses typically range from 75 mg to 150 mg daily, often split into two or three administrations. The 20 mg tablet strength of this Metenolone formulation allows for precise dosing within this range (e.g., four tablets providing 80 mg). For women, doses are much lower, usually 20 mg to 40 mg daily. Cycles can be extended to 8-12 weeks with proper monitoring.

Treatment Protocol and Monitoring

Cycles with oral Metenolone can be longer than with other orals, often 8-12 weeks, due to its low toxicity. Results are steady and gradual, focusing on quality muscle preservation and slight growth. While less stressful, monitoring is still advised and should include blood tests to check liver enzymes (though elevations are typically minor) and lipid profiles, as Metenolone can suppress HDL cholesterol. Blood pressure is rarely an issue.

Pharmacological Profile

Oral Metenolone is 1-methylated, which allows it to survive first-pass liver metabolism with significantly less hepatotoxic impact than traditional 17-alpha-alkylated compounds. It has a half-life of approximately 4-6 hours, supporting multiple daily doses for stable blood levels. It is not aromatizable and is excreted in urine.

Common Side Effects

Metenolone is renowned for one of the mildest side effect profiles among oral anabolic steroids. The most common are minimal but can include:

• Mild Androgenic Effects: Possible acne, oily skin, or hair loss only in highly predisposed individuals at high doses.
• Suppression of Natural Testosterone: Still induces suppression of the HPTA, requiring a testosterone base for men and post-cycle therapy.
• Negative Lipid Impact: Can negatively affect cholesterol by lowering HDL levels, though typically to a lesser degree than stronger orals.
• Very Low Hepatotoxicity: Liver enzyme elevations are possible but usually mild and manageable.

Metenolone does not cause estrogenic or progestogenic side effects. It is often considered one of the safest oral steroids for both men and women, with virilization risk in women being low at reasonable doses. It is contraindicated in individuals with severe pre-existing liver disease.

You can buy Metenolone made by Apoxar in bulk in Canada via our website. Navigate to the “Purchase” tab and fill the contact form with details of your wholesale order. Please note: we do not sell single packs or ship directly to consumers, Apoxar is a wholesale fitness medication manufacturer and we work exclusively with our approved distributors.